Publications

Importance of patient bed pathways and length of stay differences in predicting COVID-19 hospital bed occupancy in England

Background: Predicting bed occupancy for hospitalised patients with COVID-19 requires understanding of length of stay (LoS) in …

Quentin J. Leclerc, Naomi M. Fuller, Ruth H. Keogh, Karla Diaz-Ordaz, Richard Sekula, Malcolm G. Semple, ISARIC4C Investigators, CMMID COVID-19 Working Group, Katherine E. Atkins, Simon R. Procter, Gwenan M. Knight
DOI

Real-time monitoring of COVID-19 dynamics using automated trend fitting and anomaly detection

As several countries gradually release social distancing measures, rapid detection of new localized COVID-19 hotspots and subsequent …
Thibaut Jombart, Stephane Ghozzi, Dirk Schumacher, Timothy J. Taylor, Quentin J. Leclerc, Mark Jit, Stefan Flasche, Felix Greaves, Tom Ward, Rosalind M. Eggo, Emily Nightingale, Sophie Meakin, Oliver J. Brady, CMMID COVID-19 Working Group, Graham F. Medley, Michael Hohle, W. John Edmunds
DOI

Analysis of temporal trends in potential COVID-19 cases reported through NHS Pathways England

The National Health Service (NHS) Pathways triage system collates data on enquiries to 111 and 999 services in England. Since the 18th …
Quentin J Leclerc, Emily Nightingale, Sam Abbott, CMMID COVID-19 Working Group, Thibaut Jombart
DOI

Antimicrobial resistance and COVID-19: Intersections and implications

Before the coronavirus 2019 (COVID-19) pandemic began, antimicrobial resistance (AMR) was among the top priorities for global public …
Gwenan M Knight, Rebecca E Glover, C Finn McQuaid, Ioana D Olaru, Karin Gallandat, Quentin J Leclerc, Naomi M Fuller, Sam J Willcocks, Rumina Hasan, Esther van Kleef, Clare IR Chandler
DOI

Comparing the Analysis and Results of a Modified Social Accounting Matrix Framework with Conventional Methods of Reporting Indirect Non-Medical Costs

Background: Assessing the societal perspective in economic evaluations of new interventions requires estimates of indirect non-medical …

Baudouin Standaert, Christophe Saubouin, Quentin J. Leclerc, Mark P. Connolly
DOI

Implication of backward contact tracing in the presence of overdispersed transmission in COVID-19 outbreaks

Background: Contact tracing has the potential to control outbreaks without the need for stringent physical distancing policies, e.g. …

Akira Endo, CMMID COVID-19 Working Group, Quentin J. Leclerc, Gwenan M. Knight, Graham F. Medley, Katherine E. Atkins, Sebastian Funk, Adam J. Kucharski
DOI

What settings have been linked to SARS-CoV-2 transmission clusters?

Background: Concern about the health impact of novel coronavirus SARS-CoV-2 has resulted in widespread enforced reductions in people’s …

Quentin J. Leclerc, Naomi M. Fuller, Lisa E. Knight, CMMID COVID-19 Working Group, Sebastian Funk, Gwenan M. Knight
DOI

Feasibility of informing syndrome-level empiric antibiotic recommendations using publicly available antibiotic resistance datasets

Background: Antibiotics are most often prescribed empirically, meaning that they are used to treat infection syndromes prior to …

Quentin J. Leclerc, Nichola R. Naylor, Alexander M. Aiken, Francesc Coll, Gwenan M. Knight
DOI

Mathematical modelling to study the horizontal transfer of antimicrobial resistance genes in bacteria: current state of the field and recommendations

Antimicrobial resistance (AMR) is one of the greatest public health challenges we are currently facing. To develop effective …
Quentin J. Leclerc, Jodi A. Lindsay, Gwenan M. Knight
DOI